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Fmoc-Lys-OH hydrochloride
CAS No. 139262-23-0
Fmoc-Lys-OH hydrochloride( —— )
Catalog No. M28362 CAS No. 139262-23-0
Fmoc-Lys-OH hydrochloride is a alkyl-chain-based PROTAC linker. Fmoc-Lys-OH hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1G | 26 | In Stock |
|
Biological Information
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Product NameFmoc-Lys-OH hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionFmoc-Lys-OH hydrochloride is a alkyl-chain-based PROTAC linker. Fmoc-Lys-OH hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DescriptionFmoc-Lys-OH hydrochloride is a alkyl-chain-based PROTAC linker. Fmoc-Lys-OH hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). (In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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In VitroADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorNHE1
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Research Area——
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Indication——
Chemical Information
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CAS Number139262-23-0
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Formula Weight404.89
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Molecular FormulaC21H25ClN2O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (308.73 mM)
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SMILESCl.NCCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Guzman-Perez A, et al. Discovery of zoniporide: a potent and selective sodium-hydrogen exchanger type 1 (NHE-1) inhibitor with high aqueous solubility. Bioorg Med Chem Lett. 2001 Mar 26;11(6):803-7.
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